Agenda

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Day 1 - 14th April

09:00 Welcome address Assembly Room
 

Dame Deidre Hine (Chair, Partners Forum, Wales Cancer Institute)

09:15 Plenary Session Assembly Room
 

Chair – Professor Chris McGuigan (Welsh School of Pharmacy, Cardiff University)

The story of Clofarabine

Professor Christopher Wood (Executive Chairman, Nucana Biomed Ltd)

10:05 Plenary Session Assembly Room
 

Chair – Professor Laurence Moore (UK CRC Public Health Research Centre of Excellence, Cardiff Institute of Society, Health and Ethics, Cardiff University)

Tobacco cessation

Professor Robert West (Cancer Research UK Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London)

10:55 - 11:15 Refreshments Lower Hall, Marble Hall

Parallel Sessions

11:15 - 12:45 1) Cancer policy in Wales - Question and answer session with Key Welsh Assembly Members
 

Chair - Hywel Griffith (Health Correspondent, BBC Wales)

Panel

  • Helen Mary Jones AM (Plaid Cymru Spokesperson for Health)
  • Peter Black AM (Welsh Liberal Democrat Spokesperson for Health)
  • Panel member to be confirmed (Labour Spokesperson for Health)
  • Cath Lindley (General Manager for Wales, Macmillan Cancer Support)
  • Harpal Kumar (Chief Executive Officer, Cancer Research UK)
  • Panel member to be confirmed
11:15 - 12:45 2) Genomic instability
 

Chair - Dr Duncan Baird (CR UK Senior Fellow and Reader, School of Medicine, Cardiff University)
Co-chair – Dr Simon Reed (Non-Clinical Reader, School of Medicine, Cardiff University)

11:15 Removal of covalent bound topoisomerases from DNA by MRN and Ctp1: implications for cancer drug resistance mechanisms
 

Dr Edgar Hartsuiker (Bangor University)

11:45 Proffered papers
12:15 The effect of telomerase on the genomic instability and bystander signaling which is induced by low doses of CR (VI)
 

Dr Charles Patrick Case (Bristol Implant Research Centre, Avon Orthopaedic Centre, Southmead Hospital, Bristol)

11:15 - 12:45 3) Clinical Trials Showcase
 

Chair – Professor John Wagstaff (Director, Wales Cancer Trials Network)
Co-chair - Gareth Griffiths (Scientific Director, Wales Cancer Trials Unit)

11:20 EXCITE & ARISTOTLE Trials
 

Dr Simon Gollins (Consultant Clinical Oncologist, North Wales Cancer Treatment Centre, Rhyl)

11:40 COIN Trial
 

Professor Tim Maughan (Professor of Cancer Studies, Consultant Clinical Oncologist, Velindre Hospital, Cardiff)

12:00 FRAGMATIC Trial
 

Dr Simon Noble (Clinical Senior Lecturer in Palliative Medicine, Royal Gwent Hospital)

12:20 Modern clinical trial design and surrogate endpoints
 

Professor Marc Buyse (CEO and Founder, International Drug Development Institute, Louvain-La-Neufe, Belgium)

11:15 - 12:45 4) Palliative care: a patient orientated approach
Question & answer session
 

Chair – Stephanie Jones (Wales Cancer Trials Network Consumer representative)
Co-chair – Barbara Moore (Cancer Research UK, Wales Cancer Trials Network)

11:20 Overview of end of life care strategies across the UK and lessons for Wales
 

Dr Rachael Addicott (Senior Research Fellow, King’s Fund, London)

11:40 District nurse palliative & end of life care education project
 

Mel Lewis (Lead Nurse Palliative Care, Cardiff and Vale University Local Health Board)
Sally Anstey (Lecturer - End of life care, School of Nursing and Midwifery Studies, Cardiff University)

12:00 Establishing equitable access for patients to palliative care research: looking for a Welsh solution
 

Dr Anthony Byrne (Medical Director, Marie Curie Cancer Care)

12:20 Questions to the panel
12:45 - 14:00 Lunch and poster viewing Lower Hall, Marble Hall

Parallel Sessions

14:00 - 15:30 5) Cell signalling and human cancer
 

Chair – Professor Julian Sampson (Institute of Medical Genetics, Wales College of Medicine, Cardiff University)
Co-chair – Professor John Blenis (Professor of Cell Biology, Harvard Medical School, Harvard University, Boston, USA)

14:00 PI 3-kinase signalling in human cancer
 

Professor Peter Downes (Principal and Vice-Chancellor, University of Dundee, Dundee)

14:45 Proffered papers
14:00 - 15:30 6) Molecular Therapy  
 

Chair – Dr Richard Adams (Senior Lecturer in Clinical Oncology, Velindre Cancer Centre, Velindre Hospital, Cardiff)
Co-chair – Professor Peter Barrett-Lee (Consultant and Clinical Oncologist, Velindre Cancer Centre, Velindre Hospital, Cardiff)

14:00 Overview of personalised medicine in colorectal cancer or The COIN Trial - what has it told us?
 

Dr Richard Adams (Senior Lecturer in Clinical Oncology, Velindre Cancer Centre, Velindre Hospital, Cardiff)

14:15 Overview of personalised treatments in breast cancer - lessons from the UK ABC Trial
 

Professor Peter Barrett-Lee (Consultant and Clinical Oncologist, Velindre Cancer Centre, Velindre Hospital, Cardiff)

14:40 Lung cancer and molecular medicine
 

Dr Dean Fennell (Consultant and Senior Lecturer, Centre for Cancer Research and Cell Biology, Queens University, Belfast)

15:05 Endocrine resistance in breast cancer – new targets
 

Dr Steven Hiscox (RCUK Academic Fellow, Welsh School of Pharmacy, Cardiff University)

14:00 - 15:30 7) Drug discovery and development –
an introductory guide
 

Chair – Professor Chris McGuigan (Welsh School of Pharmacy, Cardiff University)
Co-chair – Dr Andrew Westwell (Senior Lecturer in Medicinal Chemistry, Welsh School of Pharmacy, Cardiff University)

14:00 Molecular graphics and computer visualisation in (cancer) drug discovery
 

Dr Andrea Brancale (Lecturer in Medicinal Chemistry, Welsh School of Pharmacy, Cardiff University)

14:20 Irrational drug discovery: stumbling and (sometimes) finding
 

Professor Chris McGuigan (Welsh School of Pharmacy, Cardiff University)

14:40 Testing of new anti-cancer drugs in the lab
 

Professor Alan Clarke (Professor of Mammalian Genetics, Cardiff School of Biosciences, Cardiff University)

15:00 Clinical trials of new drugs
 

Professor Alan Burnett (Head of Department - Haematology, University Hospital of Wales, Cardiff University)

15:20 Questions and answers
14:00 - 15:30 8) Picture of cancer in Wales
 

Chair – Dr Ian Lewis (Scientific Director, Tenovus)
Co-chair – to be confirmed

14:00 Cancer trends in Wales, 1991-2008
 

Dr Ceri White (Lead Statistician, Wales Cancer Intelligence Surveillance Unit)

14:20 Title of presentation to be confirmed
 

Dr Alexandra Murray (Clinical Lead, Cancer Genetics Service for Wales)

14:40 Title of presentation to be confirmed
 

Professor John Wagstaff (Director, Wales Cancer Trials Network)

15:00 Title of presentation to be confirmed
 

Professor Malcolm Mason (Director of Wales Cancer Bank)

15:20 Questions and answers
14:00 - 15:30 9) Children and young people with cancer
 

Chair – Simon Morgan-Jones (Service Manager for Wales, CLIC Sargent)
Co-chair – Michele Pengelly (Specialist Nurse, Supportive Care, Velindre Cancer Centre)

14:00 ‘More than my illness’ – What’s important to teenagers and young adults with cancer
 

Simon Morgan-Jones (Service Manager for Wales, CLIC Sargent)

14:35 The needs of children when a parent or grandparent has cancer
 

Michele Pengelly (Specialist Nurse, Supportive Care, Velindre Cancer Centre)

14:55 Questions and answers
15:30 - 15:50 Refreshment break Lower Hall, Marble Hall
15:50 Plenary Session Assembly Room
 

Chair – Dr Andrew Westwell (Senior Lecturer in Medicinal Chemistry, Welsh School of Pharmacy, Cardiff University)

Drug discovery - sponsored by British Association for Cancer Research (BACR)

Professor Laurence Hurley (Professor of Medicinal Chemistry, University of Arizona, USA)

16:40 Plenary Session Assembly Room
 

Chair – Libby Batt (Associate Director, Wales Cancer Trials Network)

The patient experience

Lynn Faulds Wood (Founder, Lynn's Bowel Cancer Campaign)

17:30 - 18:30 Poster viewing and drinks reception Lower Hall
18:30 - 20:00 Opportunities for commercially sponsored Satellite Symposia

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